The effect of butaselmevit and closaverm A on the immune status of cows with experimental fasciolosis sensitized by atypical mycobacteria

There are many reports in the literature about critical role of immune system protecting body against foreign agents. However, status association mycobacteriosis and fasciolosis has not been studied. The work aimed to investigate effect butaselmevit closaverm A on cows with experimental sensitized by atypical mycobacteria. For trial, 15 4–5 years age, black spotted breed, were selected, from which 3 groups formed, five animals each. Cows first research group for injected intramuscularly at a dose 0.5 ml drug per 10 kg weight. second group, fasciolosis, weight animal. obtained results indicate that drugs “Klosaverm A” “Butaselmevit” when administered mycobacteria, contribute activation cellular nonspecific links immunity. It should be noted number our also established stimulating humoral link immunity, particular, an increase bactericidal lysozyme activity blood serum associated fasciolosis. Using helped reduce level CIC physiological values starting 21st day experiment. according indicators combined use closer shows better therapeutic than only alone.